Cell-mediated immunity in experimental Nocardia asteroides infection.
نویسندگان
چکیده
Experimental mycetoma-like lesions developed in guinea pigs after subcutaneous injection of Nocardia asteroides. Although delayed hypersensitivity appeared earlier, increased macrophage migration inhibition and microbicidal activity appeared after 7 weeks. When the lesions healed, high cell-mediated immunity was present. Cell-mediated immunity was transferred to normal recipient guinea pigs from healed donor guinea pigs by spleen cell transfer. Recipient guinea pigs showed marked protection against challenge with N. asteroides.
منابع مشابه
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عنوان ژورنال:
- Infection and immunity
دوره 15 2 شماره
صفحات -
تاریخ انتشار 1977